Chicken Alfredo Lasagna

July 02, 2026

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Made by Zach

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This Chicken Alfredo Lasagna layers juicy seasoned chicken, rich homemade Alfredo sauce, tender pasta, and plenty of Parmigiano-Reggiano into the ultimate creamy comfort meal. It’s perfect for feeding a crowd or making ahead for busy weeknights.

Ingredients:

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Ingredients are subject to availability at local stores. Unavailable items will be automatically substituted at best-effort.

Directions

  1. Season the chicken breasts with salt, black pepper, garlic powder, onion powder, paprika, and oregano.
  2. Heat the olive oil in a skillet over medium-high heat. Cook the chicken until golden brown and fully cooked, then slice or shred and set aside.
  3. To make the Alfredo sauce, melt the butter in a saucepan over medium heat. Add the garlic and cook until fragrant.
  4. Pour in the heavy cream and milk. Bring to a gentle simmer while stirring.
  5. Remove from the heat and whisk in the Parmigiano-Reggiano until smooth. Season with salt and black pepper.
  6. Spread a thin layer of Alfredo sauce into the bottom of a baking dish.
  7. Add a layer of lasagna noodles, more Alfredo sauce, and a layer of the cooked chicken. Repeat until all ingredients have been used, finishing with Alfredo sauce and extra Parmigiano-Reggiano.
  8. Cover with foil and bake at 350–375°F for 25–35 minutes. Remove the foil during the final 10 minutes to lightly brown the top.
  9. Let the lasagna rest for 5–10 minutes before slicing and serving.

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